The /lib and /usr/lib symlink on Gentoo I find quite annoying. These just let software make assumptions about whether they should use /usr/lib or /usr/lib64 , and I personally prefer if things break so they can be fixed. I wanted to follow what RedHat (and Fedora) are doing, which is, 32-bit stuff goes in lib and 64-bit in lib64 . Luckily, Gentoo was also headed this way. So, here is what I did. First I prepare a custom profile. This profile inherits these two: default/linux/amd64/13.0/desktop/gnome/systemd , which I normally use features/multilib In the custom profile I add make.defaults with the single line SYMLINK_LIB="no" . Get rid of the lib symlink, but do it carefully. First copy everything from lib64 to lib (well, I just opted for hard linking everything): sudo rsync -avPAH --link-dest /lib64/{,} /lib.new/ sudo rsync -avPAH --link-dest /usr/lib64/{,} /usr/lib.new/ sudo bash -x -c 'rm -v /lib && mv /lib.new /lib' sudo bash -x -c 'rm -v /usr/...